In the shadow of the nation's capital, Kate Livingston holds a respectable position as a government statistician when she encounters a rival from her past, the insufferable Trevor McDonough. A Harvard-trained physician, Trevor never showed the tiniest flicker of interest in Kate, and she's bewildered at the way he suddenly seeks her out. Surprising even herself, Kate agrees to Trevor's entirely unexpected and risky proposal to work side-by-side with him in his quest to rid the world of tuberculosis, a contagious and deadly disease.