The end of the American Civil War reopened the floodgates for humanity headed west. Men and women hungered for land and business opportunities to help them rebuild their Civil war-torn lives and families. Prairie Song chronicles the beginning of the overland journey for the westbound Boones Lick Road Company, a wagon train setting out from Saint Charles, Missouri in the spring of 1866. The captain of the caravan, Garrett Cowlishaw, lived through the war, while Caroline Milburn agonized at home, fearing that her missing husband was not destined to return. Trail hand Caleb Reger carries a crushing secret from the battlefield to the road west and Anna Goben knew she could lose her brother to the war, but hadn't imagined the ruin the loss could bring to her household. Encounter these few among the families and individuals, many from the Saint Charles Quilting Circle, who have set out looking for their Promised Land. On a road marked with more suffering, will they learn that the promise remains alive in their hearts, no matter the circumstances?