Wildlife photographer Stephen Kirkpatrick's assignment is to document an area of the Amazon rain forest that has never before been photographed. Kirkpatrick sees the expedition as a golden opportunity-a trip that could change his career. But within hours of their departure, an inaccurate map and a series of bad decisions combine to leave Kirkpatrick's five-man expedition hopelessly lost in the treacherous depths of the Amazon jungle. What began as a photo shoot quickly becomes a struggle for survival.